This is a new position for a Research Associate (RA) in the Li Ka Shing Applied Virology (LKSAV) group that will report to the Medicinal Chemist. The major roles and responsibilities of this RA position will involve the synthesis of small molecules of interest.
The LKSAV Group is a collaborative research environment designed to translate and commercialize basic research discoveries. There are approximately 30 staff from varied disciplines (virologists, chemists, immunologists, computational scientists and GMP manufacturers, etc.) working in the LKSAV Group with more than 12 active projects under development for future clinical testing and commercialization. In addition, the group actively collaborates with about 12 Principal Investigators from the department of Medical Microbiology & Immunology as well as other University of Alberta departments. It also has active collaborations with 10 Principal Investigators at other Canadian & international organizations.
- Independently identify and perform potential synthetic routes to novel compounds
- Demonstrate a high level of laboratory productivity by independently synthesizing and properly characterizing target molecules identified by the project team to quickly test design theories and successfully progress drug discovery and development programs
- Troubleshoot synthetic and laboratory challenges and, with input from supervisor and more senior chemist, implement agreed upon next steps
- Follow proper record keeping to fully document results and appropriately characterize intermediates and target compounds to secure intellectual property and permit scientific publication
- Generate progress reports and present work regularly at chemistry and program team meetings
- Work with scientists from other disciplines on multi-disciplinary teams to accelerate commercialization activities
- Show good laboratory housekeeping and share responsibilities with other laboratory scientists to ensure a productive, efficient, clean and safe laboratory
- Adhere to safety procedures and instructions from Laboratory Manager, Senior Synthetic Chemist and supervisor
- Write synthetic protocols to support patent applications and publications
- PhD in Organic or Medicinal Chemistry with a synthetic chemistry focus
- Greater than 3 years industrial experience at a CRO or biotechnology company working on drug discovery projects is preferred
- Experience synthesizing and purifying organic molecules with the ability to perform the work independently
- Expert at characterizing compounds using modern tools and writing up experimental procedures
- Prior experience synthesizing nucleoside and nucleotides is preferred
- Experience maintaining laboratory equipment, such as HPLC or LC/MS is desirable
- Expert with Microsoft Office (including Excel, Word and PowerPoint), database utilization, drawing software (e.g. ChemDraw), and label production
- Excellent attention to detail, organized and excellent communication skills
- Time management skills to maximize achievements
In accordance with the Trust/Research Academic Staff Agreement, this position has a term of one year, with the possibility of renewal, and offers a comprehensive benefits package found at www.hrs.ualberta.ca and an annual salary range of $57,350 to $78,866. Salary is commensurate with experience and qualifications.
Review of applications will begin on January 11, 2017; however, the competition will remain open until a suitable candidate is hired.